BDBM50526691 CHEMBL4563913

SMILES NC(=N)NCCCCCC(=O)O[C@H]1C[C@@H](O[C@@H]1CO)n1cc([125I])c(=O)[nH]c1=O

InChI Key InChIKey=XXPWTHNTHNMLDQ-QZIRHQCUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50526691   

TargetSodium-dependent noradrenaline transporter(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50526691(CHEMBL4563913)
Affinity DataIC50: 8.20E+3nMAssay Description:Substrate activity at NET in human BE(2)-C cells assessed as inhibition of drug uptake by measuring MIBG IC50 incubated for 1 hr in presence of nonra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50526691(CHEMBL4563913)
Affinity DataIC50: 2.20E+4nMAssay Description:Substrate activity at NET in human SK-N-SH cells cells assessed as inhibition of drug uptake by measuring MIBG IC50 incubated for 1 hr in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50526691(CHEMBL4563913)
Affinity DataIC50: 2.39E+4nMAssay Description:Substrate activity at NET in human BE(2)-C cells cells assessed as inhibition of drug uptake by measuring MIBG IC50 incubated for 1 hr in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50526691(CHEMBL4563913)
Affinity DataIC50: 2.87E+4nMAssay Description:Substrate activity at NET in human BE(2)-C cells cells assessed as inhibition of drug uptake by measuring MIBG IC50 incubated for 1 hr in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50526691(CHEMBL4563913)
Affinity DataIC50: 3.52E+4nMAssay Description:Substrate activity at NET in human SK-N-SH cells cells assessed as inhibition of drug uptake by measuring MIBG IC50 incubated for 1 hr in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50526691(CHEMBL4563913)
Affinity DataIC50: 7.62E+4nMAssay Description:Substrate activity at NET in human SK-N-SH cells assessed as inhibition of drug uptake by measuring MIBG IC50 incubated for 1 hr in presence of nonra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed