BDBM50526818 CHEMBL4592435

SMILES CC(C)(C)NC(=O)C[C@H](NS(=O)(=O)C1CC1)C(=O)NCCNC(=O)c1cc(ccc1F)-c1ccccc1F

InChI Key InChIKey=GQVVEENHIHWDOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526818   

TargetProteasome subunit beta type-8(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526818(CHEMBL4592435)
Affinity DataIC50: 15nMAssay Description:Inhibition of 20S proteasome beta 5i (unknown origin) after 1 hr by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50526818(CHEMBL4592435)
Affinity DataIC50: 960nMAssay Description:Inhibition of 20S proteasome beta 5c (unknown origin) after 1 hr by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed