BDBM50526863 CHEMBL4474770

SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2cnoc12

InChI Key InChIKey=MFZKTINXWPQHBG-UHFFFAOYSA-N

Data  3 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50526863   

TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  180nMAssay Description:Binding affinity to HSP90-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  180nMAssay Description:Displacement of FITC-geldanamycin from HSP90beta (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  180nMAssay Description:Binding affinity to HSP90beta (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataIC50: 180nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataIC50: 180nMAssay Description:Inhibition of HSP90beta (unknown origin) incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmin(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  8.48E+3nMAssay Description:Binding affinity to GRP94 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEndoplasmin(Dog)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataIC50: 8.48E+3nMAssay Description:Inhibition of FITC-GDA binding to dog GRP94 incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEndoplasmin(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  8.48E+3nMAssay Description:Displacement of FITC-geldanamycin from GRP94 (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  9.55E+3nMAssay Description:Displacement of FITC-geldanamycin from HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataKd:  9.55E+3nMAssay Description:Binding affinity to HSP90alpha (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50526863(CHEMBL4474770)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of 6His-tagged human HSP90alpha N-terminal domain (1 to 223 residues) expressed in Escherichia coli BL21 DE3 cells incubated for 24 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed