BDBM50526866 CHEMBL4581355

SMILES Cc1c(F)c(Nc2ccc(cn2)-c2cn(C)cn2)cc2n(CC3CC3)cnc12

InChI Key InChIKey=INGJMHPGMVUEKY-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50526866   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to GABA-A alpha5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataKi:  24nMAssay Description:Binding affinity to GABA-A alpha3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataKi:  32nMAssay Description:Binding affinity to GABA-A alpha2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataKi:  140nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50526866(CHEMBL4581355)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed