BDBM50526894 CHEMBL4539430

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CSCc2ccccc2CSC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)NCC(=O)N[C@@H](Cc2ccc(F)cc2)C(=O)NNC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)CNC1=O

InChI Key InChIKey=VGWQFVAQTVJFHI-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50526894   

TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50526894(CHEMBL4539430)
Affinity DataEC50: <0.510nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes incubated for 1 hr by [35S]-GTPgammaS coupling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50526894(CHEMBL4539430)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human DOR expressed in CHO cell membranes incubated for 1 hr by [35S]-GTPgammaS coupling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50526894(CHEMBL4539430)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-diprenorphine from human DOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50526894(CHEMBL4539430)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-diprenorphine from human MOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50526894(CHEMBL4539430)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes incubated for 1 hr by [35S]-GTPgammaS coupling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50526894(CHEMBL4539430)
Affinity DataKi:  77nMAssay Description:Displacement of [3H]-diprenorphine from human KOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed