BDBM50527634 CHEMBL4456827

SMILES CC[C@H](Nc1ncnc(N)c1Cl)c1nc2cccc(NCc3ccc(cn3)C(=O)NO)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=CFBUBQDTEDCOTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527634   

TargetHistone deacetylase 6(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50527634(CHEMBL4456827)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells using fluorogenic pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50527634(CHEMBL4456827)
Affinity DataIC50: 189nMAssay Description:Inhibition of human PI3Kdelta assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed