BDBM50527732 CHEMBL4460451

SMILES Nc1ncc2[nH]cc(-c3cccc(c3)C#CC(O)c3nccs3)c2n1

InChI Key InChIKey=MLOOAVADQUAVKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50527732   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50527732(CHEMBL4460451)
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged NIK (318 to 947 residues) expressed in baculovirus infected Sf9 cells using ultrapure ATP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed