BDBM50527868 CHEMBL4586582

SMILES CCCN(CCCCNC(=O)c1cc2ccccc2[nH]1)C[C@H]1C[C@@H]1c1cccc(Cl)c1Cl

InChI Key InChIKey=OXKMARLXXNQVMY-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50527868   

TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-Mesulergine from recombinant human 5HT2C receptor expressed in HEKT cell membranes measured after 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataEC50:  143nMAssay Description:Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataKi:  676nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D4 receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataKi:  992nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D2 receptor stably expressed in fibroblast cell membranes measured after 90 mins by mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at D3 receptor (unknown origin) expressed in human HTLA cells assessed as induction of beta-arrestin2 recruitment measured after 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [3H]-SCH23390 from recombinant human D1 receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataEC50:  2.55E+3nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527868(CHEMBL4586582)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-SCH23390 from recombinant human D5 receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed