BDBM50527891 CHEMBL4578364

SMILES CCN(CCCSc1nnc(-c2ccccc2)n1C)CC1CC1c1cc(Cl)ccc1OC

InChI Key InChIKey=RJZDQOPJWQCJET-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50527891   

TargetD(3) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527891(CHEMBL4578364)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527891(CHEMBL4578364)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]-Mesulergine from recombinant human 5HT2C receptor expressed in HEKT cell membranes measured after 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527891(CHEMBL4578364)
Affinity DataKi:  238nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D2 receptor stably expressed in fibroblast cell membranes measured after 90 mins by mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527891(CHEMBL4578364)
Affinity DataKi:  241nMAssay Description:Displacement of [3H]-N-methylspiperone from recombinant human D4 receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527891(CHEMBL4578364)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-SCH23390 from recombinant human D1 receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50527891(CHEMBL4578364)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-SCH23390 from recombinant human D5 receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed