BDBM50528227 CHEMBL4464579

SMILES COc1cccc(CC(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3)ccc2F)c1

InChI Key InChIKey=WFWVJTWOJNJWJW-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528227   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528227(CHEMBL4464579)
Affinity DataKd:  240nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528227(CHEMBL4464579)
Affinity DataKd:  55nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed