BDBM50528483 CHEMBL4448450

SMILES Clc1ccc(Cn2cc(C(=O)N\N=C\c3ccc(cc3)C#N)c3ccccc23)cc1

InChI Key InChIKey=QFILWQMENLVEBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528483   

TargetProstaglandin G/H synthase 2(Human)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50528483(CHEMBL4448450)
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50528483(CHEMBL4448450)
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed