BDBM50528510 CHEMBL4452140

SMILES Nc1nc(SCCO)c(C#N)c(-c2cccnc2)c1C#N

InChI Key InChIKey=ZEJGBMJTWGELMY-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528510   

TargetAdenosine receptor A1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50528510(CHEMBL4452140)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cell membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50528510(CHEMBL4452140)
Affinity DataEC50:  94nMAssay Description:Inverse agonist activity at human A1AR expressed in CHO cells assessed as increase in forskolin-stimulated cAMP production by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50528510(CHEMBL4452140)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human A2B expressed in CHO cells assessed as stimulation of cAMP production by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed