BDBM50528713 CHEMBL4589725

SMILES NS(=O)(=O)Oc1ccc(NC(=O)N2CCN(CC2)c2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=WCFRJEPDEBLNCB-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50528713   

TargetSteryl-sulfatase(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50528713(CHEMBL4589725)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cell using [3H] E1S as substrate after 1 hr by scintillation spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Firenze

Curated by ChEMBL
LigandPNGBDBM50528713(CHEMBL4589725)
Affinity DataKi:  4.54E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Firenze

Curated by ChEMBL
LigandPNGBDBM50528713(CHEMBL4589725)
Affinity DataKi:  9.19E+5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Firenze

Curated by ChEMBL
LigandPNGBDBM50528713(CHEMBL4589725)
Affinity DataKi:  1.64E+6nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Firenze

Curated by ChEMBL
LigandPNGBDBM50528713(CHEMBL4589725)
Affinity DataKi:  9.03E+5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed