BDBM50528763 CHEMBL4472697

SMILES CCOP(=O)(CC)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=JMUQGCMUIAFBTI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50528763   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50528763(CHEMBL4472697)
Affinity DataIC50: 21nMAssay Description:Inhibition of IDO1 in human HeLa cells using L-tryptophan as substrate incubated for 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50528763(CHEMBL4472697)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant N-terminal His-tagged human IDO1 expressed in Escherichia coli assessed as reduction in N-formylkynurenine formation using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50528763(CHEMBL4472697)
Affinity DataIC50: 280nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50528763(CHEMBL4472697)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of N-terminal His-tagged human TDO expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed