BDBM50528792 CHEMBL4438974

SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1cccc2ncccc12)C(F)(F)F

InChI Key InChIKey=RTNNEMKUXXDIAB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50528792   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hospital of Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50528792(CHEMBL4438974)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hospital of Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50528792(CHEMBL4438974)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]RTX from recombinant human TRPV1 expressed in CHO cells incubated for 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Hospital of Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50528792(CHEMBL4438974)
Affinity DataKi:  29nMAssay Description:Binding affinity to MOR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Hospital of Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50528792(CHEMBL4438974)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-DAMGO from full length human MOR expressed in chem5 cells incubated for 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hospital of Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50528792(CHEMBL4438974)
Affinity DataEC50:  32nMAssay Description:Antagonist activity at recombinant human TRPV1 expressed in CHO cells assessed as as inhibition of capsaicin-induced calcium uptake incubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hospital of Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50528792(CHEMBL4438974)
Affinity DataKi:  32nMAssay Description:Binding affinity to human TRPV1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed