BDBM50529081 CHEMBL4450564

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCCC3)ncc2NC1=O

InChI Key InChIKey=JTYDPPQNZSHIQR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50529081   

TargetSerine/threonine-protein kinase PLK1(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50529081(CHEMBL4450564)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant full length human His-tagged PLK1 expressed in baculovirus expression system using ser/thr 16 as substrate incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50529081(CHEMBL4450564)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant full length human GST-tagged PLK2 expressed in baculovirus expression system using ser/thr 16 as substrate incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50529081(CHEMBL4450564)
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of recombinant human GST-tagged PLK3 (58 to 340 residues) expressed in baculovirus expression system using ser/thr 16 as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed