BDBM50529176 CHEMBL4581690

SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5cc(Br)cc(Br)c5)cccc4o3)c2c1

InChI Key InChIKey=PLCNWFXJRXGTOE-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529176   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Univ. Grenoble Alpes

Curated by ChEMBL

LigandBDBM50529176(CHEMBL4581690)Copy SMILESCopy InChI

Affinity DataEC50:  97nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as increase in mitoxantrone accumulation incubated for 30 mins by flow cytome...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL