BDBM50529422 CHEMBL4447753

SMILES Cc1ccccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br

InChI Key InChIKey=NIGSHUCAVVQZLX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50529422   

TargetShort transient receptor potential channel 5(Human)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of (-)-Englerin-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 5(Human)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of lanthanum-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 5(Human)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 5(Human)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of riluzole-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Goldfinch Bio

Curated by ChEMBL
LigandPNGBDBM50529422(CHEMBL4447753)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of OAG-activated human TRPC6 channel expressed in HEK293 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed