BDBM50529943 CHEMBL4442152

SMILES Cc1ccc(CNC(=O)[C@@H]2COCCCCCCCn3ccnc3C(=O)N[C@@H](CC(=O)NCC(C)(C)C)C(=O)N2)cc1

InChI Key InChIKey=SRKZSDFHGYHOFA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50529943   

TargetProteasome subunit beta type-8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 19nMAssay Description:Inhibition of human peripheral blood derived 20s immunoproteasome beta5 chymotrypsin-like activity using Suc-PAL-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 19nMAssay Description:Inhibition of human peripheral blood derived 20s immunoproteasome beta5 chymotrypsin-like activity using Suc-PAL-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 34nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta5 chymotrypsin-like activity using Suc-WLA-AMC as substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 34nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta5 chymotrypsin-like activity using Suc-WLA-AMC as substrate preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta1 caspase-like activity using Suc-LLE-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human peripheral blood derived 20s immunoproteasome beta1 caspase-like activity using Suc-PAL-AMC as substrate preincubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta2 trypsin-like activity using Suc-LLE-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human peripheral blood derived 20s immunoproteasome beta1 caspase-like activity using Suc-PAL-AMC as substrate preincubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta1 caspase-like activity using Suc-LLE-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50529943(CHEMBL4442152)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human hepatic cell derived 20s constitutive proteasome beta2 trypsin-like activity using Suc-LLE-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed