BDBM50530002 CHEMBL4532398

SMILES C[C@@H]1CN(CCO1)C(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(CCCCCCC(=O)NO)c2n1

InChI Key InChIKey=YPXRCUVTZDXVHY-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50530002   

TargetHistone deacetylase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant full length HDAC3 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant full length HDAC3 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC11 expressed in baculovirus expression system using Ac-peptide-AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC7 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC11 expressed in baculovirus expression system using Ac-peptide-AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC9 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC7 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50530002(CHEMBL4532398)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC9 expressed in baculovirus expression system using Ac-peptide-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed