BDBM50530563 CHEMBL4519938::US11337971, Compound (R)-19
SMILES CCc1cccc(N2CCN(C[C@H](O)CCNC(=O)c3cc4ccccc4[nH]3)CC2)c1Cl
InChI Key InChIKey=OIRZLTZLOKARTG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50530563
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 0.245nMAssay Description:Binding at dopamine D2-like receptors was determined using previously described methods. Membranes were prepared from HEK293 cells expressing human D...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 0.290nMAssay Description:Binding at dopamine D2-like receptors was determined using previously described methods. Membranes were prepared from HEK293 cells expressing human D...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [125I] DOI from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [125I] DOI from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I] DOI from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I] DOI from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 68.1nMAssay Description:Binding at dopamine D2-like receptors was determined using previously described methods. Membranes were prepared from HEK293 cells expressing human D...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 75.8nMAssay Description:Binding at dopamine D2-like receptors was determined using previously described methods. Membranes were prepared from HEK293 cells expressing human D...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 76nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataKi: 76nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 248nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 248nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataEC50: 1.05E+3nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataEC50: 1.05E+3nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataEC50: >2.20E+3nMAssay Description:Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataEC50: >2.20E+3nMAssay Description:Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of quinpirole-induced mitogenesisMore data for this Ligand-Target Pair