BDBM50530641 CHEMBL4572065

SMILES Fc1ccc(cc1)-c1nc(sc1-c1ccnc(Nc2ccncn2)n1)C1CCNCC1

InChI Key InChIKey=XQLHPFMGKSLXAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50530641   

TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530641(CHEMBL4572065)
Affinity DataIC50: 12nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530641(CHEMBL4572065)
Affinity DataIC50: 12nMAssay Description:Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530641(CHEMBL4572065)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50530641(CHEMBL4572065)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed