BDBM50531299 CHEMBL4454608

SMILES COc1ccc(cc1)-c1cc(-c2cccc(Br)c2)c(C#N)c(N)n1

InChI Key InChIKey=VRGKDTFQDYCZFO-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531299   

TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531299(CHEMBL4454608)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cells incubated for 50 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531299(CHEMBL4454608)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cells incubated for 50 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531299(CHEMBL4454608)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human A1AR expressed in CHO-K1 cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531299(CHEMBL4454608)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human A1AR expressed in CHO-K1 cells assessed as reduction in NECA-induced inhibition of forskolin-stimulated cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531299(CHEMBL4454608)
Affinity DataKi:  3.80E+4nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cells after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50531299(CHEMBL4454608)
Affinity DataKi:  3.80E+4nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cells after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed