BDBM50531369 CHEMBL4533192

SMILES ONC(=O)CCCCCCNC(=O)c1c(sc2cc(O)ccc12)-c1ccc(O)cc1

InChI Key InChIKey=YVLBUPXOCBVXFQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50531369   

TargetHistone deacetylase 3(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 128nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 168nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 214nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 596nMAssay Description:Inhibition of recombinant human FLAG/His-tagged HDAC1 expressed in baculovirus expression system using Boc-l-Lys(Ac)-AMC as substrate preincubated up...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 665nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 719nMAssay Description:Inhibition of HDAC8 (unknown origin) expressed in Escherichia coli using BML-KI-178 as substrate preincubated up to 3 hrs and measured after 35 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50531369(CHEMBL4533192)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of recombinant human full-length HDAC2 expressed in baculovirus expression system using Boc-l-Lys(Ac)-AMC as substrate preincubated up to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed