BDBM50531610 CHEMBL4559706

SMILES C=CC(=O)Nc1cccc(c1)-n1c2c(ccc1=O)oc1ccc(cc21)-c1cccnc1

InChI Key InChIKey=FVCDPGCMEGFTQT-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531610   

TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50531610(CHEMBL4559706)Copy SMILESCopy InChI

Affinity DataIC50: 74nMAssay Description:Inhibition of BTK (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50531610(CHEMBL4559706)Copy SMILESCopy InChI

Affinity DataIC50: 170nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50531610(CHEMBL4559706)Copy SMILESCopy InChI

Affinity DataIC50: 855nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50531610(CHEMBL4559706)Copy SMILESCopy InChI

Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50531610(CHEMBL4559706)Copy SMILESCopy InChI

Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetSerine/threonine-protein kinase mTOR(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50531610(CHEMBL4559706)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTOR (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL