BDBM50531923 CHEMBL4462126

SMILES CC(C1CC1)n1cnc2c(NCc3cccc(c3)C(F)(F)F)nc(NCCN(C)C)nc12

InChI Key InChIKey=GHRNSZVMIARHIS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531923   

TargetCasein kinase I isoform alpha(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50531923(CHEMBL4462126)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant full length human GST-tagged CK1apha expressed in baculovirus using peptide as substrate after 3 hrs by kinase-glo luminesc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50531923(CHEMBL4462126)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant full length C-terminal human His-tagged CDK7/cyclin H/N-terminal MAT1 expressed in baculovirus expression system using Cdk7...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50531923(CHEMBL4462126)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant N-terminal human GST-tagged CK1delta (1 to 294 residues) expressed in Escherichia coli using RKKKAEpSVASLTSQCSYSS peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50531923(CHEMBL4462126)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of CDK2 (unknown origin) after 3 hrs by kinase-glo luminescent assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50531923(CHEMBL4462126)
Affinity DataIC50: 8.30E+5nMAssay Description:Inhibition of MAPK8 (unknown origin) using peptide as substrate after 3 hrs by kinase-glo luminescent assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50531923(CHEMBL4462126)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full-length human MAPK1 expressed in Escherichia coli using MBP1 as substrate after 3 hrs by kinase-g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed