BDBM50531943 CHEMBL4580295

SMILES CCC1(CC)c2ccc(cc2Oc2cc3ccc(cc3cc12)-c1cnc([nH]1)[C@@H]1CCCN1C[C@@H](NC(=O)OC)C1CCOCC1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C1CCOCC1

InChI Key InChIKey=RDPYORRNCUPPGH-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50531943   

TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.0500nMAssay Description:Inhibition of NS5A Y93H mutant in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.0300nMAssay Description:Inhibition of NS5A in HCV genotype 1b assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.0600nMAssay Description:Inhibition of NS5A in HCV genotype 3a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.0300nMAssay Description:Inhibition of NS5A in HCV genotype 2b assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.00700nMAssay Description:Inhibition of NS5A in HCV genotype 4a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.00700nMAssay Description:Inhibition of NS5A L31V mutant in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Merck

Curated by ChEMBL
LigandPNGBDBM50531943(CHEMBL4580295)
Affinity DataEC50:  0.00300nMAssay Description:Inhibition of NS5A in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed