BDBM50532266 CHEMBL4467344

SMILES B1(c2ccc(cc2CO1)Oc3ccc(c(c3)C#N)C#N)O

InChI Key InChIKey=UBMGTTRDNUKZMT-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50532266   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50532266(CHEMBL4467344)
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDE4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50532266(CHEMBL4467344)
Affinity DataIC50: 240nMAssay Description:Inhibition of human PDE4B1 expressed in baculovirus infected sf9 cells incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50532266(CHEMBL4467344)
Affinity DataIC50: 240nMAssay Description:Inhibition of human PDE4B1 expressed in baculovirus infected sf9 cells incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)