BDBM50532564 CHEMBL4456288

SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OC)-c1ccncc1

InChI Key InChIKey=VGZZYWAKZYKCPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532564   

TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532564(CHEMBL4456288)
Affinity DataIC50: 1.40nMAssay Description:Displacement of 125I-ET1 from human placenta cell membrane ETA receptor expressed in Baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50532564(CHEMBL4456288)
Affinity DataIC50: 1.40nMAssay Description:Displacement of 125I-ET1 from human placenta cell membrane ETA receptor expressed in Baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed