BDBM50532633 CHEMBL4449425

SMILES Nc1nccc(n1)N1CC[C@@H](C1)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=LMHRTURPPBEGGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532633   

TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532633(CHEMBL4449425)
Affinity DataIC50: 42nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCyclin-C(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50532633(CHEMBL4449425)
Affinity DataIC50: 42nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed