BDBM50532707 CHEMBL4585968

SMILES COc1nonc1OCCOc1ccc(cc1)-c1ccc(CN2CCc3cc(OC)c(OC)cc3C2)cc1

InChI Key InChIKey=PJOQAKOMOGXSFR-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532707   

TargetATP-dependent translocase ABCB1(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50532707(CHEMBL4585968)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50532707(CHEMBL4585968)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50532707(CHEMBL4585968)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of BCRP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50532707(CHEMBL4585968)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of BCRP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed