BDBM50532867 CHEMBL4518126

SMILES C[C@H](N)C(=O)NCc1ccc(Oc2ccc(F)cc2)c(C)c1

InChI Key InChIKey=INEFYTXJRINZJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532867   

TargetHistone-arginine methyltransferase CARM1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50532867(CHEMBL4518126)
Affinity DataIC50: 270nMAssay Description:Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50532867(CHEMBL4518126)
Affinity DataIC50: 270nMAssay Description:Inhibition of full-length Halo-tagged human CARM1 (1 to 608 residues) expressed in 293-F cells using [3H]-SAM and biotinylated histone peptides by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50532867(CHEMBL4518126)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PRMT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50532867(CHEMBL4518126)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PRMT6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed