BDBM50532998 CHEMBL4587231

SMILES COc1cc(CCn2cnc3sc4CN(CCc4c3c2=O)C(=O)C(F)(F)F)cc(OC)c1

InChI Key InChIKey=MEFNUCYNHDRJFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532998   

TargetP2X purinoceptor 3(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50532998(CHEMBL4587231)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetP2X purinoceptor 3(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50532998(CHEMBL4587231)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed