BDBM50533143 CHEMBL4458354

SMILES Clc1ccc(COc2ccc(cc2)-c2cc([nH]n2)C(=O)N\N=C\c2c[nH]c3ccccc23)cc1

InChI Key InChIKey=CSXUQZMURGRPLY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50533143   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50533143(CHEMBL4458354)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus infected Hi5 cells using L-leucine 7-amido-4-methyl coumarin as substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50533143(CHEMBL4458354)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus infected Hi5 cells using L-leucine 7-amido-4-methyl coumarin as substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50533143(CHEMBL4458354)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in baculovirus infected Hi5 cells using L-leucine 7-amido-4-methyl coumarin as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50533143(CHEMBL4458354)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in baculovirus infected Hi5 cells using L-leucine 7-amido-4-methyl coumarin as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50533143(CHEMBL4458354)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected Hi5 cells using L-Arginine 7-amido-4-methyl coumarin as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50533143(CHEMBL4458354)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected Hi5 cells using L-Arginine 7-amido-4-methyl coumarin as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed