BDBM50533157 CHEMBL4561645

SMILES CNC(=O)Nc1cc(Oc2c(F)cccc2F)c(cn1)C1CC1

InChI Key InChIKey=YUYQXJJCKOEZRT-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50533157   

TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533157(CHEMBL4561645)
Affinity DataEC50:  38nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533157(CHEMBL4561645)
Affinity DataEC50:  38nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533157(CHEMBL4561645)
Affinity DataEC50:  1.23E+3nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ and glucose 6-phosphate 4% human serum album...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533157(CHEMBL4561645)
Affinity DataEC50:  1.23E+3nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ and glucose 6-phosphate 4% human serum album...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed