BDBM50533177 CHEMBL4531223

SMILES CNC(=O)Nc1cc(Oc2cncc(C)c2)c(cn1)-c1ccc(OC[C@H](C)O)nc1

InChI Key InChIKey=IUJYIMVTOYKANW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533177   

TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533177(CHEMBL4531223)
Affinity DataEC50:  45nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50533177(CHEMBL4531223)
Affinity DataEC50:  45nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed