BDBM50533340 CHEMBL4585935

SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ncccn1

InChI Key

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50533340   

TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533340(CHEMBL4585935)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I][Tyr14]nociceptin/orphanin FQ from human nociceptin opioid receptor expressed in CHO cell membranes after 1 hr by microplate sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533340(CHEMBL4585935)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human nociceptin opioid receptor expressed in CHO cell membranes after 30 mins by GTPgamma(35)S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533340(CHEMBL4585935)
Affinity DataKi:  972nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membranes after 1 hr by microplate scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed