BDBM50533467 CHEMBL4441282

SMILES Nc1ncnc2n(nc(I)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=BZFGDXJGWSIYQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533467   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50533467(CHEMBL4441282)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of DOT1L (unknown origin) using chicken nucleosome as substrate in presence of [3H]SAM incubated for 1 hr by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50533467(CHEMBL4441282)
Affinity DataIC50: 40nMAssay Description:Inhibition of human adenosine kinase assessed as reduction in conversion of adenosine to AMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed