BDBM50533495 CHEMBL4542476

SMILES CCn1nc2c(CCC2(C)C)c1Nc1nc(cs1)-c1ccc(c(F)c1)-n1cnc(C)c1

InChI Key InChIKey=WTAHCIYSWXNHHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533495   

TargetPresenilin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50533495(CHEMBL4542476)
Affinity DataIC50: 62nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells overexpressing wild-type human APP751 assessed as inhibition of Abeta42 level after 24 hrs by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed