BDBM50533582 CHEMBL4562653

SMILES COC(=O)N[C@H](NC(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc2cc(ccc2c1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C1CCOCC1)C1CCOCC1

InChI Key InChIKey=UGPGGLRZHVFWGS-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50533582   

TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533582(CHEMBL4562653)
Affinity DataEC50:  0.113nMAssay Description:Inhibition of HCV genotype 1b replicons NS5A infected in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533582(CHEMBL4562653)
Affinity DataEC50:  0.130nMAssay Description:Inhibition of HCV genotype 1a replicons NS5A infected in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50533582(CHEMBL4562653)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of HCV genotype 3a replicons NS5A infected in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed