BDBM50533657 CHEMBL4474529

SMILES Cn1nc(cc1NC(=O)Nc1ccc(Oc2ncnc3[nH]ncc23)c(F)c1)C(C)(C)C

InChI Key InChIKey=PFLVNYYIZYFWMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533657   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50533657(CHEMBL4474529)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed by baculovirus in Sf21 insect cells measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed