BDBM50533728 CHEMBL4578210

SMILES Nc1cccc(Cl)c1C(=O)NCC1(CCCCC1)N1CCN(CC1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=JLZNBYZIAGAXSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533728   

LigandPNGBDBM50533728(CHEMBL4578210)
Affinity DataIC50: 9.36E+3nMAssay Description:Inhibition of glycine transporter-1B in human JAR cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50533728(CHEMBL4578210)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human glycine transporter-2 expressed in HEK293 cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed