BDBM50533751 CHEMBL4536223

SMILES Clc1ccc(C(=O)NCC2(CCCCC2)N2CCN(CC2)S(=O)(=O)CC2CC2)c(Cl)c1

InChI Key InChIKey=VJLVVCSODSTMLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533751   

LigandPNGBDBM50533751(CHEMBL4536223)
Affinity DataIC50: 57nMAssay Description:Inhibition of glycine transporter-1B in human JAR cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50533751(CHEMBL4536223)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human glycine transporter-2 expressed in HEK293 cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed