BDBM50533815 CHEMBL4434704

SMILES COc1ccc2NC(=O)C(=Cc3ccc4c(n[nH]c4c3)-c3ccc(nc3)N3CCN(C)CC3)c2c1

InChI Key InChIKey=TVRYEYSLCUPRPL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50533815   

TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533815(CHEMBL4434704)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533815(CHEMBL4434704)
Affinity DataIC50: 28nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533815(CHEMBL4434704)
Affinity DataIC50: 35nMAssay Description:Inhibition of AURKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
LigandPNGBDBM50533815(CHEMBL4434704)
Affinity DataIC50: 630nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50533815(CHEMBL4434704)
Affinity DataIC50: 700nMAssay Description:Inhibition of AURKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed