BDBM505340 US11040966, Example 7.53::{(S)-2-[1-(2-Methoxy-ethyl)-5,6-dimethyl-1H-benzoimidazol-2-yl]-2-methyl-pyrrolidin-1-yl}-(3'-methoxy-4-methyl-biphenyl-2-yl)-methanone

SMILES COCCn1c(nc2cc(C)c(C)cc12)C1CCCN1C(=O)c1cc(C)ccc1-c1cccc(OC)c1

InChI Key InChIKey=QLSRRRKGDHMVAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505340   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM505340({(S)-2-[1-(2-Methoxy-ethyl)-5,6-dimethyl-1H-benzoi...)
Affinity DataIC50: 46nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM505340({(S)-2-[1-(2-Methoxy-ethyl)-5,6-dimethyl-1H-benzoi...)
Affinity DataIC50: 190nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent