BDBM50534168 CHEMBL4442891

SMILES Cn1c2nc3CN(CCn3c2c(=O)n(C)c1=O)c1cccc(Cl)c1

InChI Key InChIKey=HJXMNEXKEFWFHF-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50534168   

TargetAmine oxidase [flavin-containing] B(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataIC50: 251nMAssay Description:Inhibition of recombinant rat MAO-B preincubated for 30 mins followed by addition of p-tyramine as substrate measured over 45 mins by Amplex Red MAO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataIC50: 385nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 30 mins followed by addition of p-tyramine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataKi:  557nMAssay Description:Displacement of [3H]MSX from A2A receptor in rat brain striatum membranes measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-603 from human A2B receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataKi:  8.86E+3nMAssay Description:Displacement of [3H]MSX from human A2A receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 30 mins followed by addition of p-tyramine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50534168(CHEMBL4442891)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB-11 from human A3 receptor expressed in CHO cell membrane by liquid scintillation counting method relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed