BDBM50534238 CHEMBL4516443

SMILES CC#CCn1c(nc2N3CCN=C3N(Cc3cccc(c3)C#N)C(=O)c12)N1CCC[C@@H](N)C1

InChI Key InChIKey=GJCUSMOAKRMQRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534238   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50534238(CHEMBL4516443)
Affinity DataIC50: 11nMAssay Description:Inhibition of DPP4 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 50 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50534238(CHEMBL4516443)
Affinity DataIC50: 7.85E+4nMAssay Description:Inhibition of FAP (unknown origin) using Nle-Pro-AMC as substrate preincubated for 20 mins followed by substrate addition measured after 40 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed