BDBM50534339 CHEMBL4593948

SMILES ONC(=O)[C@H](Cc1ccccc1)n1nnc(c1C#Cc1ccccc1)-c1ccccc1

InChI Key InChIKey=JMEPDOCHFSIAAG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50534339   

TargetHistone deacetylase 8(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in sf9 cells using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus expression system using fluorophore-conjugated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human C-terminal His-tagged HDAC3 expressed in sf9 cells co-expressing human N-terminal GST-tagged NCOR2 (395 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Boston University

Curated by ChEMBL
LigandPNGBDBM50534339(CHEMBL4593948)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 cells using fluorophore-conjugated substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed