BDBM50535039 CHEMBL4587034

SMILES CC(=O)Nc1cncc(c1)-c1cc(c[nH]1)C(=O)c1c(Cl)cccc1Cl

InChI Key InChIKey=BLUGZEWNYPNWEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535039   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50535039(CHEMBL4587034)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DOTL1 (2 to 416 residues)-mediated methylation of nucleosome preincubated for 30 mins followed by addition of S-[methyl-3H-] aden...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed