BDBM50535077 CHEMBL4579018

SMILES CC(C)=CCc1c(O)c(CC=C(C)C)c2c(c1O)C(=O)C[C@@H](c1ccc(O)cc1O)O2

InChI Key InChIKey=LITAWVYVXARFNJ-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50535077   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535077BDBM50535077(CHEMBL4579018)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells incubated for 6 hrs by p-dimethylaminobenzaldehyde reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535077BDBM50535077(CHEMBL4579018)
Affinity DataKd:  6.50E+3nMAssay Description:Binding affinity to wild type human His-tagged IDO1 expressed in Escherichia coli T7 by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535077BDBM50535077(CHEMBL4579018)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli T7 incubated for 1 hrs by p-dimethylaminobenzaldehyde reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sunchon National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535077BDBM50535077(CHEMBL4579018)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of kynuramine ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sunchon National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535077BDBM50535077(CHEMBL4579018)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 10 mins followed by addition of benzylamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed